Disease liability from deep neural networks

Disease liability from deep neural networks

In this study, we computed disease liabilities from deep neural networks and introduced liability and meta-GWAS methods leveraging these scores to explore genetic associations in binary traits.

Disease liability from deep neural networks

Yang, L.*, Sadler, M.C.* & Altman, R.B. Genetic association studies using disease liabilities from deep neural networks. Am J Hum Genet 112, 675–692 (2025).